Introduction
- Cancer is the second leading cause of death in America (10) and modern treatments have not greatly improved, causing researchers to search for less harmful and invasive solutions (5).
- Exercise may be a beneficial solution to prevent the spread cancer, without the harsh side effects of traditional treatments (6).
- Regulatory T Cells
- Treg cells are immune effector cells that are made by the thymus to prevent autoimmunity by suppressing the immune response (5).
- Treg cells try to avoid unnecessary tissue damage via suppressing various immune cells (9).
- After exercise, the amount of Treg cells in circulation increases (6), however they can promote tumor regressions and activate tumor-protective Treg cells (5).
- Treg cells are immune effector cells that are made by the thymus to prevent autoimmunity by suppressing the immune response (5).
- Our research is attempting to find the relationship between the immune system during cancer and exercise, and to see how the cells benefit the body. We will use a rat spleens and tumors to measure the concentration of Treg cells with and without an exercise routineInsert intro that's edited here